Name this sign

Test your knowledge with the May 2018 Brain Teaser

By Phil Zeltzman, DVM, DACVS, CVJ, Fear Free Certified

 

Answers:

1. When a mast cell tumor is physically manipulated during an exam, degranulation occurs. This triggers the release of histamine, which causes vasodilatation, erythema and hive formation.
2. This is called “Darier’s sign.”
3. The name comes from the French dermatologist Ferdinand-Jean Darier (1856–1938) who first described it.

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